Causes for acute kidney injury ATIN: Pre renal causes (most common): Volume depletion (defective intravascular volume) : Acute tubular necrosis it changed to ATIN ( acute tubule interstitial nephritis): Criteria for defining ATIN: KDIGO stage 1: KDIGO stage 2: KDIGO stage 3: Site of tubular injury in ATIN: S3 segment of proximal straight tubule > … Read more
Chronic kidney disease- introduction: CKD: decrease number of functioning nephrons GFR: single nephrons GFR * number of functional nephrons Interstitial fibrosis tubular atrophy glomerular sclerosis TGF- beta: key molecule in pathogenesis of CKD Chronic kidney disease- causes: Causes of CKD Rate of fall of GFR Diabetic nephropathy 8-10 ml/min/year Chronic glomerular nephropathy 6-8 ml/min/year Ischemic … Read more
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